Everyone deserves the option of better mental health
Small Pharma is a biotechnology company researching and developing short-duration psychedelics with supportive therapy for mental health conditions.
Everyone deserves the option of better mental health
Small Pharma is a biotechnology company researching and developing short-duration psychedelics with therapy for under-served mental health conditions.
Today’s antidepressants leave a third of patients behind. This mental health epidemic needs solutions, not wishful thinking.
Peter Rands
Co-Founder, Small Pharma
We’re on a mission to fast track the development of short-duration psychedelic therapies for patients affected by depression and other mental health conditions .
We believe people deserve treatments that work quickly, have long lasting benefits and are well tolerated. So we're taking a radically different approach.

Who we are,
what we do
Find out more about our story and meet the team behind Small Pharma
‘We do have to start looking for a completely different approach, and try something completely out of the box.’
Dr Carol Routledge, CMSO
It has been a real pleasure working with Small Pharma since the launch of Drug Science’s Medical Psychedelics Working Group in July 2020. Small Pharma have been a partner since the beginning, together we have achieved much and have far-reaching plans for the future.
Prof Jo Neill
Scientific Committee at Drug ScienceTraditional talk therapy can be extremely expensive and for some it takes years to process their psychological issues. Often it is those rare experiential moments when a re-enactment of old wounds surfaces that provide a real shift in the therapeutic process. Psychedelics can provide those experiential moments and thus hold great potential in catalysing therapy.
Michelle Baker Jones
Study Therapist on Small Pharma's clinical trialSmall Pharma’s endeavour to test psychedelic therapy for depression is not only interesting and timely but also very important. Their ambitious research program has the potential to make a positive difference for patients suffering depression.
Dr David Erritzoe
Clinical Director at the Centre for Psychedelic ResearchOur approach
A novel approach to drug development, by innovating on known compounds to create new and protectable mental health treatments.
Our goal is to develop treatments that provide fast-acting relief, with long-lasting effects, that are scalable in-clinic treatments.

Our goal is to develop treatments that:
provide fast-acting relief
provide long-lasting effects
are scalable in-clinic

Our Approach
Accelerated drug development
We innovate on known compounds. This allows us to accelerate and reduce the risk of early drug development to ultimately speed up progress to trial potential medicines in human clinical trials.
Scalability
We focus on progressing therapies that have the potential to become scalable treatments in critical areas of unmet need, such as depression.
Fast-acting, long-lasting
Our goal is to develop optimized therapies for patients that target better outcomes than current treatments on offer, with rapid and durable relief.
Robust IP protection
We have a robust and multi-layered IP program to protect our innovation.


Our focus is short-duration psychedelics
Psychedelics with supportive therapy may have potential as antidepressant treatments.
Research to date has shown great potential with psychedelics in treating mental health conditions. Psychedelic compounds vary in their duration of subjective effects, often referred to as 'the psychedelic experience', which can range from minutes to more than 12 hours. We want to create scalable in-clinic mental health treatments, so we're focused on short-duration psychedelics with supportive therapy.
Research & trials

Years of R&D development
Medicines in development
Active clinical trials
Investor News
Small Pharma Announces Significant Developments In Intellectual Property Portfolio
5 new patent grants with 3 expected upcoming patent grants in May.
Small Pharma Announces Positive Six-month Data from Phase IIa Trial of SPL026
Patients who achieved remission within three months sustained remission to six months.
Small Pharma announces further positive data from SPL026 Phase IIa trial in Major Depressive Disorder strengthening topline efficacy results
Statistically significant improvement in anxiety symptoms offers potential in indications beyond depression.