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Powerful hallucinogenic drug used in shamanic rituals is being trialled in the UK as a cure for DEPRESSION

  • The hallucinogenic drug DMT is being trialled on British depression patients 
  • It is hoped it will help bring relief to those who don’t respond to normal pills 
  • Evidence suggests that DMT in combination with talking therapy can help 

A powerful hallucinogenic drug that has been used in shamanic rituals is being trialled by a British firm as a potential cure for depression.

Small Pharma will give volunteers suffering from depression DMT, a hallucinogenic tryptamine with similar psychedelic effects to LSD and magic mushrooms.

The developers hope the drug will help a ‘significant number’ of people who don’t currently respond to conventional treatments or medication for depression.

One of the active ingredients of DMT is ‘ayahuasca’ which is a traditional Amazonian plant medicine used ritually by some tribes to bring ‘spiritual enlightenment’.

An increasing body of evidence has shown that when combined with talking therapy, hallucinogenic drugs can be a safe treatment for a range of mental illnesses.

‘We believe the impact will be almost immediate, and longer lasting than conventional antidepressants,’ Carol Routledge from Small Pharma told the BBC.

Small Pharma hopes that the treatment will not only act quickly to support patients with depression, but also bring longer-term relief.

This is the first time DMT has been given to patients with moderate to severe depression during a clinical trial in the UK.


About Small Pharma

We’re a mental health drug development company that’s accelerating the development of fast acting antidepressant treatments using DMT based therapies. We’re dedicated to making a difference.

With a focus on innovative approaches and committed to challenging the status quo, we’re targeting the root causes of depression and hoping to unlock the minds of millions.

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